Combined therapy ameliorated proteinuria and glomerulosclerosis mostly as a result of the action of Altace. Altace attenuates left ventricular remodeling by regulating the expression of activin A-follistatin in a rat model of heart failure. All 6213 individuals with type 2 diabetes without macroalbuminuria from the Ongoing Telmisartan Alone and in Combination With Altace Global Endpoint Trial (ONTARGET) were included in this observational study.
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