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As a result, compound 8e was identified to be the most potent inhibitor against wild-type influenza A virus, being nearly 240-fold more active than Amantadine. Recently, a substantial increase in Amantadine-resistant strains has been reported, most of which have a substitution at amino acid position 31 in the M2 gene.

Other names for this medication:
Amantadine, Symmetrel, Aman, Amantadina, Amantan, Amixx, Antadine, Lysovir, Mantadan, Mantadix, Protexin, Symadine, Tregor, Viregyt, Virosol,

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Amantadine is used to prevent or treat a certain type of flu (influenza A). If you have been infected with the flu, this medication may help make your symptoms less severe and shorten the time it will take you to get better. Taking amantadine if you have been or will be exposed to the flu may help to prevent you from getting the flu. This medication is an antiviral that is believed to work by stopping growth of the flu virus. This medication is not a vaccine. To increase the chance that you will not get the flu, it is important to get a flu shot once a year at the beginning of every flu season, if possible. Based on the recommendation from the Centers for Disease Control (CDC) in the US, amantadine should not be used to treat or prevent influenza A because the current influenza A virus in the United States and Canada is resistant to this medication. For more details, talk to your doctor or pharmacist. Amantadine is also used to treat Parkinson's disease, as well as side effects caused by drugs (e. g. , drug-induced extrapyramidal symptoms), chemicals, other medical conditions. In these cases, this medication may help to improve your range of motion and ability to exercise. For the treatment of these conditions, amantadine is believed to work by restoring the balance of natural chemicals (neurotransmitters) in the brain.

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acetobutylicum glcG gene appears to be associated with a BglG-type regulator mechanism, as it is preceded by a transcription terminator that is partially overlapped by a typical ribonucleic antiterminator (RAT) sequence, and is downstream of an open reading frame that appears to encode a transcription antiterminator protein. Bombesin-like peptides stimulate gastrin release from isolated rat G-cells. The subjects of this study were 40 female sophomores (21 for the ESGI, 19 for the FSGI).

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Moreover, respondents completed demographic questions, the Health-Risk Attitude Scale (HRAS), the Expectations Regarding Aging (ERA) questionnaire, questions about beliefs regarding future health (i.e. The presence of bronchocentric granulomatosis in the biopsy of a mass does not exclude the presence of an accompanying bronchogenic carcinoma associated with obstruction of bronchioles. Electronic based interaction between patients and health care professionals will provide unique opportunities as well as challenges in efforts towards improving the quality of and access to health care services. We show that Rab12 is activated in a stimulus-dependent fashion and promotes microtubule-dependent retrograde transport of the SGs in the activated cells. According to the circumstances, the diaphragm will adapt towards a slow profile (COPD, cardiac failure and in animals: Duchenne muscular dystrophy, denervation-1 week, age-female, corticosteroids, chronic stimulation), or a fast profile (in animals: chronic hypoxia, denervation-2 weeks, age-males) or a more oxidative profile (in animals: cachexia, obesity).

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Different methods of preparation and concentration of saliva specimens were discussed. Column leaching experiments were carried out to evaluate the dependence of the leached amount of DOC on Ca leaching. Pediatric patients resuscitated from SCD appear to remain at risk for recurrence of life-threatening tachyarrhythmias.

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Evolution recruited old hands from existing signaling pathways to guide and accomplish the extraordinary task of repeatedly building and destroying this highly specialized tissue. High dose-rate brachytherapy of prostate cancer utilising Iridium-192 after-loading technique: technical and methodological aspects.

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This article reviews the literature to indicate evidence for the impact of hospital unit design on nurse/patient visibility relations and to identify design parameters shown to affect visibility. This suggests an important role for the synovial antigen presenting cell in the aetiology of inflammatory joint diseases. These results indicated that familial investigations including plasma calcitonin measurements after pentagastrin stimulation, are valuable when amyloid stroma MTC is diagnosed in one member of the family.

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Thus, male mating calls may elicit vocalizations from the female, but are less effective than male odor cues. The patient recovered satisfactorily without any serious neurological deficits after the operation. Rosiglitazone attenuates angiotensin II-induced C-reactive protein expression in hepatocytes via inhibiting AT1/ROS/MAPK signal pathway.

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IL-10 and IL-12 are the main regulatory cytokines in visceral leishmaniasis. Lactate dehydrogenase activity was measured by chemical colorimetric method.

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The increased mucosal uptake of ionized iron was not the result of increased adsorption, but instead appeared related to a metabolically active uptake process, whereas the increased mucosal uptake of transferrin iron was associated with increased numbers of mucosal cell membrane transferrin receptors. Efficient synthetic protocols for the preparation of common N-heterocyclic carbene precursors. The renal lysozyme level continued to rise during the first 4 weeks after hypophysectomy and then remained constant while the serum level increased immediately after hypophysectomy and plateaued. The chemoprophylactic effects of halofuginone lactate were tested against calf experimental cryptosporidiosis. The finding of a variable skills level before and a variable development during internship indicates that teaching in practical procedures is unstructured and inadequate.

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PAL31, a novel nuclear protein, expressed in the developing brain. Impact of the biocide Irgarol on meiofauna and prokaryotes from the sediments of the Bizerte lagoon-an experimental study.

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The effect of RES blockade on cellular antibody formation to sheep erythrocytes. Relative humidity was found to have no effect on the performance of the FTIR over the range studied. The positions of both the reduced and the oxidized sulphur are described. We determined if the ellipsoid zone (EZ) disruption pattern could be predictive of the geographic atrophy (GA) pattern at 1 year in dry age-related macular degeneration (AMD).

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This information can help to cast light on the potential disease mechanisms of breast cancer. A simple cryopreservation method for the maintenance of cell viability and mechanical integrity of a cultured cartilage analog. Hospitals are realizing that a singular focus on the needs of physicians can leave nurses out in the cold. Using this assay, no ATM mutations were found in our patient population. Although endoscopic third ventriculostomy is considered to be a simple and safe procedure, one should be aware that severe and sometimes fatal complications may occur.

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The effects of a pediatric unilateral inguinal hernia clinical pathway on quality and cost. Interferon inhibitory activity (IIA) is a logical candidate for explaining neutralizing antibody-negative partial responsiveness to interferon beta in multiple sclerosis (MS), but its role has not been evaluated. In this article I list a number of ingredients that are necessary in any effective psychotherapy.

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We investigated the possibility to extract information based on in-room CT images (kVCT, MVCT), acquired for daily image-guided radiotherapy treatment of head-and-neck cancer patients, in order to predict individual response in terms of toxicity. IgG2 antibodies dominated the antibody response to the lipopolysaccharide of the bacterium. Two weeks post-operatively, the cells close to that matrix had polarized nuclei and a clear distal area with minute processes, suggestive of preodontoblasts.

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At the same time a dramatic rise in the total and non-sedimentable activities of some lysosomal hydrolases was recorded under the above conditions. The aim of this study was to investigate RHOA transcription and copy number changes in three epithelial tumors (breast, renal cell and epithelial ovarian carcinomas, 45 tumor/normal pairs altogether). Clinical results of radiofrequency hyperthermia combined with radiation in the treatment of radioresistant cancers. As hapten inhibitors, glycopeptides prepared by pronase-digestion of various glycoproteins (porcine submaxillary mucin, bovine submaxillary mucin, and porcine thyroglobulin), and several glycosides of D-galactose and 2-acetamido-2-deoxy-D-galactose were employed.

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Introgression was traced in both sexes but gene flow may be slightly male-biased. Purified (auto)antibodies also bound nonspecifically to band 4.2 and weakly to band 5 and 6, when assayed with second antibody and 125I-iodinated protein A.

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The results indicated that YJ-37 reacted with sialylated lacto-series carbohydrate chains, which have been reported to accumulate in cancer cells. Intracoronary radiolabeled microspheres were injected and coronary arteriograms were quantitatively analyzed by semiautomated methods.

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It is concluded that in male guinea pigs the time around sexual maturity is crucial for the development of social skills necessary to arrange with unfamiliar conspecifics in a nonstressful way. Tissue reaction and influenza virus infectiousness during multiplication in tissue culture in the presence of remantadine

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An example of the use of nonphysicians in providing health primary care in Sarawak is outlined. Molecular cloning and characterization of a unique 60 kDa/72 kDa antigen gene encoding enzyme I of the phosphoenolpyruvate: sugar phosphotransferase system (PTS) of Mycoplasma hyopneumoniae. The mean of the initial Out response was significantly greater absolutely than that of the In response. It was also shown that hydrogen peroxide leads to an increase in the activities of both catalases and Cu,Zn-containing SOD. Field studies of vertebrates suggest, and laboratory experiments on invertebrates confirm, that even when males provide no material benefits, polyandry can enhance offspring survival.

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High-frequency intensity modulation in orthogonal polarized dual frequency lasers with optical feedback. This article explores the different challenges in the development, validation, and application of prediction models in CKD. The bacterially expressed 15K protein was used to raise antibodies in rabbits. The bone from the rabbits to which sodium fluoride had been administered showed a higher Ca/P ratio than that from untreated control animals by both of the methods of assessment. This study examines functional characteristics of platelets from stressed rats in more detail.

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It is acknowledged as having an unspecific granulomatous inflammatory nature in different locations. Ethylenethiourea (ETU) is a ubiquitous impurity of the ethylenebisdithiocarbamate (EBDC) fungicides widely used in agriculture and forestry. These experiments performed on samples of cylindrical and spherical nanopore geometries demonstrate that the average diffusion coefficient parallel to the interface is proportional to the pore radii in different dynamics regimes. There were no significant differences in the levels of Gla in urine before or during the treatment.

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Reaching the hard-to-reach: illicit drug use among high school absentees. Intercavernous sinus venography was performed on 12 cases of pituitary microadenomas. Population substructure was assessed using Eigenstrat and ADMIXTURE software for both platforms. flavus were also examined through reciprocal crosses between sclerotia and conidia. Open subtrochanteric osteotomy in children, correcting the colodiaphyeal angle and the length of the femur

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Gas exchange dynamics with sinusoidal work in young and elderly women. Clinical remission of adenocarcinoma of the ovary induced by triethylene thiophosphoramide. A time-efficient algorithm mapped measured oxygenation changes in a three-dimensional volume to allow surgeons and clinical personnel to detect and localize abnormal blood perfusion changes during or after surgery, in time for corrective intervention.

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For this reason the colour match of all the free-flap donor sites in our investigation is poorer. CI-I inhibited the decrease of ikappaBalpha expression in RAW264.7 cells treated with LPS. The normal response of increased plasma insulin following high-intensity exercise is also not present in the L-citrulline condition, indicating that L-citrulline ingestion may reduce nitric oxide-mediated pancreatic insulin secretion or increased insulin clearance.

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The metabolic activity of the protoplasts and normal cells of Saccharomyces cerevisiae and the effect of inhibitors. Future studies should use computerized cognitive assessment, measures of functional genetic polymorphisms, and neuroimaging techniques, in order to further elucidate the neurochemical substrates of cognition and optimize treatment approaches. The ethical status of the child in family and child psychotherapy

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Clinicopathologic and pathologic findings were consistent with a diagnosis of malabsorption and protein-losing enteropathy, attributable to lymphocytic and plasmacytic infiltration of the intestine. VIP-LI axons also formed synapses on non-immunoreactive dendrites or dendritic spines. Glycodelin-A is a glycoprotein abundant in the decidua during early pregnancy. Also in granule cells activated by joint movements did we find indications that different afferents were driven by the same type of input.

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We report a simple, two-step method (phosphocellulose and immunoaffinity column chromatographies) for purification of the mouse DNA polymerase alpha-primase complex. Argon laser indirect ophthalmoscope photocoagulation has been used as an alternative to cryotherapy, with fewer adverse effects.

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The 45, X/46, XY mosaicism presents with a wide spectrum of phenotypes with the highest proportion of being genital ambiguity. Metaanalysis of randomized controlled studies suggest that topiramate may be the most potent of the new antiepileptic drugs and have a favourable pharmacokinetic profile.

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Plasma total homocysteine levels in postmenopausal women with unstable coronary artery disease. This study represents the first broad examination of immune function in a free-ranging pinniped population.

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In dermatological practice, the variation is assumed to be even higher. However, MMW radar speech is often degraded by combined sources of noise, which mainly include harmonic, electrical circuit and channel noise. In order to illustrate the great diversity of clinical signs, each case is individually presented. contortus L3 despite otherwise unfavourable environmental conditions. In 90 patients, 63 with 2 to 5 years of follow-up, using the surgical technique described, the Baker III/IV capsular contracture rate was 5.6 percent.

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Deficits in conditioned avoidance responding following adrenalectomy and central norepinephrine depletion are dependent on postsurgical recovery period and phase of the diurnal cycle. Control branches continued to stiffen even after diameter growth stopped. Expression of human DNA methyltransferase 1 in colorectal cancer tissues and their corresponding distant normal tissues.

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The effects of ankle guards and taping on joint motion before, during, and after a squash match. Hepatocyte damage in autoimmune hepatitis (AIH) and chronic viral hepatitis C (CVH) is attributed to an immune response. The roles and regulation of these two isoenzymes in the root nodule are discussed.

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When seedlings were transplanted into either wet or dry potting mix in the greenhouse, ABA increased leaf resistance and leaf water potential. Veterans reported significantly poorer HRQoL than nonveterans, but when controlling for other factors, veteran status was only a significant determinant of TTO and SG health values at baseline. Deep brain stimulation for treatment-resistant depression: a psychiatric perspective. Signs and symptoms of thyroid disease can be masked by pregnancy. In patients who have had polyethylene or SFSs of varying sizes, approximately 1 in 4 have SACs.

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Members of the serpin family of serine proteinase inhibitors play important roles in the inflammatory, coagulation, fibrinolytic, and complement cascades. While HPA-1 genotyping a large cohort of patients with thromboembolic disease with a thermal cycler (LightCycler), one patient was identified with a unique HPA-1a melting curve.

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Proceedings: The use of logistic analysis to distinguish between normal and pre-eclamptic patients. Additionally, NCs can inhibit interferon signaling response and function in cell stress response, such as inducing apoptosis. Muscle orad to the site of denervation appeared subsensitive, while muscle caudad to the lesion was supersensitive (circular) or unaffected (longitudinal). The usual co-payment associated with PBS medicine is not charged and the pharmacist remuneration structure is different.

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Repetition, order of presentation, and timing of arguments and measures as determinants of opinion change. In rats, exposure to 200 or 100 ppm resulted in maternal toxicity (clinical signs, decreased body weight and weight gain, decreased absolute and relative organ weights, decreased food and water consumption and evidence of anemia), embryotoxicity (increased number of totally resorbed litters and decreased number of viable implantations per litter) and fetotoxicity (reductions in skeletal ossification). To evaluate the technical success and clinical outcome of the percutaneous treatment of acute renal vein thrombosis (RVT). The majority of this increase occurs in the region about 300 umeters beneath the sporangium.

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Reliability of speech and language therapists using therapy outcome measures. In normotensive patients with diabetes mellitus type II, the institution of angiotensin-converting enzyme inhibition during early stages of diabetic nephropathy results in long-term stabilization of plasma creatinine levels and of the degree of urinary loss of albumin. The effectiveness of re-employment programmes for unemployed persons with severe mental health problems on health and quality of life: a systematic review and meta-analysis. The scalloped dental implant (NobelPerfect, Nobel Biocare, Yorba Linda, CA, USA) is designed to biologically guide and facilitate interproximal bone remodeling during healing and to maintain bone height and papillae during functional loading.

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Reflux correction at the time of diagnosis as a substitute for traditional management. The influence of physiological parameters on long term heart rate variability in healthy preterm infants.

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Analysis of potential porcine endogenous retrovirus transmission to baboon in vitro and in vivo. The system consists of two different interactive interfaces connected through a network, for a real-time low latency video conference using audio, video, skeletal, and depth data streams from a Microsoft Kinect. The neurotoxic effect exerted on neurons needs to be considered as possible outcomes for the use of suramin in humans. Urotensin II transiently decreased coronary flow, then induced sustained vasodilatation.

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The sporocidal activities of hydrogen peroxide and formaldehyde were the lowest. Inhibition of erythroid colony growth in vitro by serum from patients with disseminated bronchial cancer. ghrelin activated several hypothalamic nuclei, including the ARC, paraventricular nucleus (PVH) and the lateral hypothalamus (LH). On the effects of psychostimulants, antidepressants, and the antiparkinsonian drug levodopa on dopamine neurons.

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Feedback from trainees across the specialties was positive, but more needs to be done to engage clinical supervisors across the range of specialties. High-frequency radio energy is applied to tissue therapeutically in a number of different medical applications. Some immunological and biochemical indices in children with rheumatism and chronic tonsillitis

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A retrospective review of 30 patients undergoing revision spinal fusion with redirection of pedicle screws was performed. Lactate dehydrogenase-elevating virus replication, maturation, and viral RNA synthesis in primary mouse macrophage cultures. The authors have presented the diagnostic and methods of treatment of soft tissue sarcomas.

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A short course of recombinant human growth hormone treatment stimulates osteoblasts and activates bone remodeling in normal human volunteers. These polymers were capable of significant delivery of siRNA against FVII and mRNA-encoding erythropoietin (EPO) in mice. In addition, the combined loss of both Tcfap2a and Tcfap2caccelerates embryonic lethality compared to the loss of either gene alone, demonstrating that genetic redundancy exists between these two AP-2 family members during the peri-implantation period of embryogenesis. After studying the receptive field properties, the afferent inputs of the neurones were studied by determining their latency of response to electrical stimulation at different positions along the optic pathway. Furthermore, the protein profiles of the Matsumoto isolates pradif t 400 retard strength were also similar to those of B.

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Plants carrying these genes respond to inoculation by Agrobacterium strains mutated at genes 1 and 2 in a virulent fashion. The incidence of the acquired immunodeficiency syndrome (AIDS) is rising at an alarming rate. Structure, function, and molecular genetics of actonel dosage forms of spironolactone erythroid membrane skeletal protein 4.1 in normal and abnormal red blood cells.

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The fetal circadian pacemaker is not involved in the timing of birth in hamsters. The maltase activity of enzyme preparations glioten tablets apple of yeasts used for baking Genetic reassortment between avian and human influenza A viruses in Italian pigs.

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We showed that HEXIM1 BR peptide depolarizes mitochondrial membrane potential in a p53-dependent manner and its cell-killing activity is not terbinafine 250mg tablets effectiveness suppressed by caspase inhibition. Characterization of PIP1 revealed that it is a PR protein closely related to Rcr3, a tomato apoplastic cysteine protease that functions in fungal resistance.

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Ethylene production rate was 1.0 nanoliter per gram fresh weight per hour in the material from the rural site and 1.5 nanoliters per gram fresh weight ledion dreamz vs pacific emaxx bodies per hour in material from the urban site. To investigate these, we analyzed clinical, neuropsychological, and electroencephalographic (EEG) data from 110 ECT-treated patients with schizophrenia and schizoaffective disorders, comparing responders with nonresponders.

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Contraction-relaxation cyp2c8 amiodarone dose of collagen fibers in LiBr-water-acetone solutions. Stability of citrated caffeine solutions for injectable and enteral use.

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However, the managed care influence was insignificant in explaining cost variation between sites due to higher morbidity in the FSS site post managed care. Whether they act locally to facilitate sodium excretion and how much importance they have compared to circulating ANP remain to be clarified. He had other causes of acute pancreatitis excluded by clinical history, serum toxicology and abdominal imaging. These results suggest that SeV is less effective than hPIV1 in overcoming antiviral metrolotion or metrogel reviews activity in human cells, which could be one of the factors that restrict the host range of SeV.

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The presented smart textile systems exhibit good performance and versatility for custom demand production. Activated protein C resistance and cardiolipin antibodies in leg ulcers One hundred and six eyes of 56 normal subjects were investigated using the Orbscan II. When the addition of streptomycin was delayed until 24 hr after the addition of tetracycline, the antibiotics acted synergistically on intracellular brucellae. One type showed no false positives with amlodipine besylate tablet usp 2.5mg erythrocyte-free urine, and no false negatives with a urine erythrocyte concentration of 20 X 10(6)/l using 5-10 X 10(6)/l as limit.